Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol
نویسندگان
چکیده
منابع مشابه
Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol
BACKGROUND Increasing energy costs and environmental concerns have motivated engineering microbes for the production of "second generation" biofuels that have better properties than ethanol. RESULTS AND CONCLUSION Saccharomyces cerevisiae was engineered with an n-butanol biosynthetic pathway, in which isozymes from a number of different organisms (S. cerevisiae, Escherichia coli, Clostridium ...
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n-Butanol has several favourable properties as an advanced fuel or a platform chemical. Bio-based production of n-butanol is becoming increasingly important for sustainable chemical industry. Synthesis of n-butanol can be achieved via more than one metabolic pathway. Here we report the metabolic engineering of Saccharomyces cerevisiae to produce n-butanol through a synergistic pathway: the endo...
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15 صفحه اولMetabolic engineering of Thermoanaerobacterium saccharolyticum for n-butanol production.
The thermophilic anaerobe Thermoanaerobacterium saccharolyticum JW/SL-YS485 was investigated as a host for n-butanol production. A systematic approach was taken to demonstrate functionality of heterologous components of the clostridial n-butanol pathway via gene expression and enzymatic activity assays in this organism. Subsequently, integration of the entire pathway in the wild-type strain res...
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ژورنال
عنوان ژورنال: Microbial Cell Factories
سال: 2008
ISSN: 1475-2859
DOI: 10.1186/1475-2859-7-36